Hyperhomocysteinemia

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Thrombophilia in hyperhomocysteinemia

A 23-year-old otherwise healthy male presented with development of painful blackish discoloration of the right thumb and index finger and of the right big toe and area over the ankle (Figs. 1 and 2), as well as painful swelling of both lower limbs, especially on the right side (Fig. 3). Homans′sign was present bilaterally. His past history was not significant. Routine investigations, including ...

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Hyperhomocysteinemia in Stroke

Homocysteine, a sulfur-containing amino acid, is an intermediate during the conversion of methionine to cysteine. Homocysteine can cause vascular injury and atherosclerotic plaque instability. In addition, homocysteine may be directly correlated with hyperlipidemia and lipoprotein(a) and inversely with highdensity lipoprotein cholesterol. However, the results regarding the association of homocy...

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[Hyperhomocysteinemia and cardiometabolic risk].

Hyperhomocysteinemia, when considered as a causal factor of vascular diseases, has been subject of much discussion. Case-control, retrospective and prospective studies have identified a relationship between high plasma concentrations of homocysteine and vascular disease. The aim of the present review was to better understand the interrelation between plasma concentrations of homocysteine and va...

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Genetic basis of hyperhomocysteinemia.

Homocysteine is a sulfur-containing, nonproteinogenic amino acid biosynthesized from methionine which has a key place in common between the folate cycle and the activated methyl cycle. Homocysteine export into the extracellular medium reflects an imbalance between homocysteine production and metabolism (1). Hyperhomocysteinemia has been associated with folate or cobalamine deficiencies, and als...

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Hyperhomocysteinemia and Left Ventricular Thrombus

© 2017 Annals of Cardiac Anaesthesia | Published by Wolters Kluwer Medknow The Editor, We read with great interest the article – Left ventricular mass: A tumor or a thrombus diagnostic dilemma, describing the narrated differential diagnosis.[1] Left ventricular thrombus formation is commonly observed in patients with myocardial infarction with systolic dysfunction. However, it becomes difficult...

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ژورنال

عنوان ژورنال: American Journal of Clinical Pathology

سال: 1997

ISSN: 1943-7722,0002-9173

DOI: 10.1093/ajcp/108.1.115